» I Have Been Using (protopic) Ointment. I Heard That Its Give Skin Cancer?

August 31st, 2009I Have Been Using (protopic) Ointment. I Heard That Its Give Skin Cancer?

i heard that protopic ointment can cause skin cancer should i continue to use it? i dont want to put myself at risk

quijibor Says:
August 31st, 2009 at 11:59 am
The Black box warning placed on Protopic was done as a precaution. There have been no cases of cancer reported that were definitely caused by the use of Protopic.
Curr Allergy Asthma Rep. 2006 Jul;6(4):270-4.
Safety of topical calcineurin inhibitors in atopic dermatitis: evaluation of the evidence.Spergel JM, Leung DY.
Topical calcineurin inhibitors (pimecrolimus, Elidel, East Hanover, NJ; and tacrolimus, Protopic, Tokyo, Japan) have been approved for the use in atopic dermatitis since the year 2000. These compounds represent a relatively safe class of topical anti-inflammatory, nonsteroidal therapy. However, in January of 2006, the US Food and Drug Administration issued a black box warning on these compounds about possible concerns of increased long-term malignancy risk due to systemic immunosuppression. To date, studies from clinical trials, systemic absorption, and post-marketing surveillance show no evidence for this systemic immunosuppression or increased risk for any malignancy.
PMID: 16822378
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red2red Says:
August 31st, 2009 at 3:36 pm
I havent heard that and my Aunt is a nurse and she said that it is ok to use
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